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- Title
Treatment of acute hepatitis C: the success of monotherapy with (pegylated) interferon alpha.
- Authors
Wiegand, Johannes; Deterding, Katja; Cornberg, Markus; Wedemeyer, Heiner
- Abstract
Early control in the acute phase of hepatitis C infection is an attractive therapeutic goal in order to shorten disease duration and infectivity, to prevent chronicity and progression to advanced liver disease and to avoid eventual therapeutic non-response in the later stages of chronic hepatitis C. Over the past decade, different interferon-based treatment options have been developed, which lead to sustained virological response rates of up to 98%. The present article summarizes the successful invention of immediate and delayed strategies in acute hepatitis C monoinfection, critically discusses potential limitations and illustrates the therapeutic challenges of the near future.
- Publication
The Journal of antimicrobial chemotherapy, 2008, Vol 62, Issue 5, p860
- ISSN
1460-2091
- Publication type
Journal Article
- DOI
10.1093/jac/dkn346