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- Title
Substitution of rifapentine for rifampin during intensive phase treatment of pulmonary tuberculosis: study 29 of the tuberculosis trials consortium.
- Authors
Dorman, Susan E; Goldberg, Stefan; Stout, Jason E; Muzanyi, Grace; Johnson, John L; Weiner, Marc; Bozeman, Lorna; Heilig, Charles M; Feng, Pei-Jean; Moro, Ruth; Narita, Masahiro; Nahid, Payam; Ray, Susan; Bates, Edward; Haile, Betial; Nuermberger, Eric L; Vernon, Andrew; Schluger, Neil W; Tuberculosis Trials Consortium
- Abstract
Rifapentine administered 5 days per week has potent activity in mouse models of antituberculosis chemotherapy, but efficacy and safety data are limited in humans. We compared the antimicrobial activity and safety of rifapentine vs rifampin during the first 8 weeks of pulmonary tuberculosis treatment.
- Publication
The Journal of infectious diseases, 2012, Vol 206, Issue 7, p1030
- ISSN
1537-6613
- Publication type
Journal Article
- DOI
10.1093/infdis/jis461