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- Title
Reduced inflammation and CD4 loss in acute SHIV infection during oral pre-exposure prophylaxis.
- Authors
Kersh, Ellen N; Luo, Wei; Zheng, Qi; Adams, Debra R; Hanson, Debra; Youngpairoj, Ae S; Cong, Mian-er; Butler, Katherine; Hendry, R Michael; McNicholl, Janet M; Heneine, Walid; Garcia-Lerma, J Gerardo
- Abstract
The impact of pre-exposure prophylaxis (PrEP) with antiretrovirals on breakthrough HIV or SHIV infection is not fully documented. We addressed the hypothesis that SHIV(SF162P3) infection despite active PrEP results in altered early immune parameters, compared with untreated infection.
- Publication
The Journal of infectious diseases, 2012, Vol 206, Issue 5, p770
- ISSN
1537-6613
- Publication type
Journal Article
- DOI
10.1093/infdis/jis422