We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Antiviral inhibitory capacity of CD8+ T cells predicts the rate of CD4+ T-cell decline in HIV-1 infection.
- Authors
Yang, Hongbing; Wu, Hao; Hancock, Gemma; Clutton, Genevieve; Sande, Nellia; Xu, Xiaoning; Yan, Huiping; Huang, Xiaojie; Angus, Brian; Kuldanek, Kristin; Fidler, Sarah; Denny, Thomas N; Birks, Jacqueline; McMichael, Andrew; Dorrell, Lucy
- Abstract
Rare human immunodeficiency virus type 1 (HIV-1)-infected individuals who maintain control of viremia without therapy show potent CD8+ T-cell-mediated suppression of viral replication in vitro. Whether this is a determinant of the rate of disease progression in viremic individuals is unknown.
- Publication
The Journal of infectious diseases, 2012, Vol 206, Issue 4, p552
- ISSN
1537-6613
- Publication type
Journal Article
- DOI
10.1093/infdis/jis379