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Title
Waning intestinal immunity after vaccination with oral poliovirus vaccines in India.
Authors
Grassly, Nicholas C; Jafari, Hamid; Bahl, Sunil; Sethi, Raman; Deshpande, Jagadish M; Wolff, Chris; Sutter, Roland W; Aylward, R Bruce
Abstract
The eradication of wild-type polioviruses in areas with efficient fecal-oral transmission relies on intestinal mucosal immunity induced by oral poliovirus vaccine (OPV). Mucosal immunity is thought to wane over time but the rate of loss of protection has not been examined.
Publication
The Journal of infectious diseases, 2012, Vol 205, Issue 10, p1554