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- Title
Hepatitis C virus infection and hepatic stellate cell activation downregulate miR-29: miR-29 overexpression reduces hepatitis C viral abundance in culture.
- Authors
Bandyopadhyay, Sarmistha; Friedman, Robin C; Marquez, Rebecca T; Keck, Kathy; Kong, Benjamin; Icardi, Michael S; Brown, Kyle E; Burge, Christopher B; Schmidt, Warren N; Wang, Yulei; McCaffrey, Anton P
- Abstract
Chronic hepatitis C virus (HCV)-induced liver fibrosis involves upregulation of transforming growth factor (TGF)-β and subsequent hepatic stellate cell (HSC) activation. MicroRNAs (miRNAs) regulate HCV infection and HSC activation.
- Publication
The Journal of infectious diseases, 2011, Vol 203, Issue 12, p1753
- ISSN
1537-6613
- Publication type
Journal Article
- DOI
10.1093/infdis/jir186