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- Title
Shifting genetic structure of invasive serotype 19A pneumococci in the United States.
- Authors
Beall, Bernard W; Gertz, Robert E; Hulkower, Rachel L; Whitney, Cynthia G; Moore, Matthew R; Brueggemann, Angela B
- Abstract
Following 7-valent conjugate vaccine introduction in the United States in 2000, invasive serotype (sero19A) pneumococcal disease (IPD) emerged rapidly. Sero19A IPD incidence increased slightly during 2005-2008 (from 2.3 cases to 2.5 cases per 100,000 population), whereas sero19A penicillin resistance (defined as a minimum inhibitor concentration [MIC] ≥2 μg/mL) increased significantly (from 28.7% to 43.7%). To better understand changes, we characterized sero19A isolates recovered during 2004-2008.
- Publication
The Journal of infectious diseases, 2011, Vol 203, Issue 10, p1360
- ISSN
1537-6613
- Publication type
Journal Article
- DOI
10.1093/infdis/jir052