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- Title
DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational age at birth.
- Authors
Lee, Hwajin; Jaffe, Andrew E; Feinberg, Jason I; Tryggvadottir, Rakel; Brown, Shannon; Montano, Carolina; Aryee, Martin J; Irizarry, Rafael A; Herbstman, Julie; Witter, Frank R; Goldman, Lynn R; Feinberg, Andrew P; Fallin, M Daniele
- Abstract
Gestational age at birth strongly predicts neonatal, adolescent and adult morbidity and mortality through mostly unknown mechanisms. Identification of specific genes that are undergoing regulatory change prior to birth, such as through changes in DNA methylation, would increase our understanding of developmental changes occurring during the third trimester and consequences of pre-term birth (PTB).
- Publication
International journal of epidemiology, 2012, Vol 41, Issue 1, p188
- ISSN
1464-3685
- Publication type
Journal Article
- DOI
10.1093/ije/dyr237