Your institution may have access to this item. Find your institution then sign in to continue.
Title
How do chemotherapeutic agents damage the ovary?
Authors
Morgan, S; Anderson, R A; Gourley, C; Wallace, W H; Spears, N
Abstract
Chemotherapy treatment in premenopausal women is associated with an increased risk of premature ovarian failure (POF) but the exact mechanism through which this occurs is uncertain. In this review we examine the current evidence for the direct action of chemotherapeutic agents on the ovary and discuss possible molecular pathways through which follicle loss may occur.
Publication
Human reproduction update, 2012, Vol 18, Issue 5, p525