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- Title
Cell-free fetal nucleic acids in amniotic fluid.
- Authors
Hui, L; Bianchi, D W
- Abstract
Research into cell-free fetal (cff) nucleic acids has primarily focused on maternal plasma; however, cff DNA and RNA are also detectable in other body fluids such as amniotic fluid (AF). In AF, cff DNA is present in much greater concentrations than in maternal plasma and represents a pure fetal sample uncontaminated by maternal- and trophoblast-derived nucleic acids. The aim of this review was to summarize the current knowledge on cff nucleic acids in AF and to outline future research directions.
- Publication
Human reproduction update, 2011, Vol 17, Issue 3, p362
- ISSN
1460-2369
- Publication type
Journal Article
- DOI
10.1093/humupd/dmq049