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- Title
Regulatory T-cells and immune tolerance in pregnancy: a new target for infertility treatment?
- Authors
Guerin, Leigh R; Prins, Jelmer R; Robertson, Sarah A
- Abstract
Adaptation of the maternal immune response to accommodate the semi-allogeneic fetus is necessary for pregnancy success, and disturbances in maternal tolerance are implicated in infertility and reproductive pathologies. T regulatory (Treg) cells are a recently discovered subset of T-lymphocytes with potent suppressive activity and pivotal roles in curtailing destructive immune responses and preventing autoimmune disease.
- Publication
Human reproduction update, 2009, Vol 15, Issue 5, p517
- ISSN
1460-2369
- Publication type
Journal Article
- DOI
10.1093/humupd/dmp004