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- Title
Psychological stress and reproductive aging among pre-menopausal women.
- Authors
Bleil, M E; Adler, N E; Pasch, L A; Sternfeld, B; Gregorich, S E; Rosen, M P; Cedars, M I
- Abstract
Life history models suggest that biological preparation for current versus longer term reproduction is favored in environments of adversity. In this context, we present a model of reproductive aging in which environmental adversity is proposed to increase the number of growing follicles at the cost of hastening the depletion of the ovarian reserve over time. We evaluated this model by examining psychological stress in relation to reproductive aging indexed by antral follicle count (AFC), a marker of total ovarian reserve. We hypothesized that stress would be related to (i) higher AFC in younger women, reflecting greater reproductive readiness as well as (ii) greater AFC loss across women, reflecting more accelerated reproductive aging.
- Publication
Human reproduction (Oxford, England), 2012, Vol 27, Issue 9, p2720
- ISSN
1460-2350
- Publication type
Journal Article
- DOI
10.1093/humrep/des214