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- Title
Association between inhibited binding of folic acid to folate receptor alpha in maternal serum and folate-related birth defects in Norway.
- Authors
Boyles, A L; Ballard, J L; Gorman, E B; McConnaughey, D R; Cabrera, R M; Wilcox, A J; Lie, R T; Finnell, R H
- Abstract
Folic acid intake during pregnancy can reduce the risk of neural tube defects (NTDs) and perhaps also oral facial clefts. Maternal autoantibodies to folate receptors can impair folic acid binding. We explored the relationship of these birth defects to inhibition of folic acid binding to folate receptor α (FRα), as well as possible effects of parental demographics or prenatal exposures.
- Publication
Human reproduction (Oxford, England), 2011, Vol 26, Issue 8, p2232
- ISSN
1460-2350
- Publication type
Journal Article
- DOI
10.1093/humrep/der144