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- Title
In vitro post-meiotic germ cell development from human embryonic stem cells.
- Authors
Aflatoonian, B; Ruban, L; Jones, M; Aflatoonian, R; Fazeli, A; Moore, H D
- Abstract
Investigating the mechanisms of human primordial germ cell (PGC) and gamete development are important for understanding the causes of infertility and effects of environmental chemicals on reproductive development. However, there are practical and ethical difficulties associated with obtaining human tissue in early development. The aim of this study was to investigate whether human embryonic stem cell-hESC-generated germ cells could provide an in vitro model of gamete development.
- Publication
Human reproduction (Oxford, England), 2009, Vol 24, Issue 12, p3150
- ISSN
1460-2350
- Publication type
Journal Article
- DOI
10.1093/humrep/dep334