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- Title
Sperm FISH studies in seven male carriers of Robertsonian translocation t(13;14)(q10;q10).
- Authors
Anton, E; Blanco, J; Egozcue, J; Vidal, F
- Abstract
Robertsonian translocation t(13;14) is one of the most common structural reorganization in humans, but meiotic segregation studies in these carriers are still limited. The segregation pattern of the chromosomes involved, the possible influence of the translocated chromosomes on the synapsis and disjunction of other chromosome pairs [interchromosomal effects (ICE)] and the rates of unbalanced spermatozoa produced still deserve attention, not only to obtain a better characterization of the meiotic behaviour of this reorganization, but also to offer carrier couples accurate genetic counselling.
- Publication
Human reproduction (Oxford, England), 2004, Vol 19, Issue 6, p1345
- ISSN
0268-1161
- Publication type
Journal Article
- DOI
10.1093/humrep/deh232