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- Title
Intracytoplasmic sperm injection pregnancy with fetal trisomy 9p resulting from a balanced paternal translocation.
- Authors
Meschede, D; Louwen, F; Eiben, B; Horst, J
- Abstract
Infertile men who carry a chromosomal translocation can be successfully treated with intracytoplasmic sperm injection (ICSI). However, such treatment carries a risk that a pregnancy with an abnormal karyotype will be induced. While in all previously published cases the outcome was favourable, we here report the first instance of a parental reciprocal translocation leading to a chromosomally unbalanced ICSI pregnancy. The fetus, one of a pair of dizygotic twins, was found to have trisomy for the short arm of chromosome 9. The parents opted for selective abortion of the affected twin.
- Publication
Human reproduction (Oxford, England), 1997, Vol 12, Issue 9, p1913
- ISSN
0268-1161
- Publication type
Journal Article
- DOI
10.1093/humrep/12.9.1913