Works matching AU Hoeijmakers, J. H. J.

Results: 122
    1

    Hybrid Molecular and Functional Micro-CT Imaging Reveals Increased Myocardial Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice.

    Published in:
    Molecular Imaging & Biology, 2024, v. 26, n. 4, p. 628, doi. 10.1007/s11307-024-01902-4
    By:
    • van Thiel, Bibi S.;
    • de Boer, Martine;
    • Ridwan, Yanto;
    • de Kleijnen, Marion G. J.;
    • van Vliet, Nicole;
    • van der Linden, Janette;
    • de Beer, Isa;
    • van Heijningen, Paula M.;
    • Vermeij, Wilbert P.;
    • Hoeijmakers, Jan H. J.;
    • Danser, A. H. Jan;
    • Kanaar, Roland;
    • Duncker, Dirk J.;
    • van der Pluijm, Ingrid;
    • Essers, Jeroen
    Publication type:
    Article
    2
    3
    4
    5
    6
    7
    8
    9

    The small CRL4<sup>CSA</sup> ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50584-7
    By:
    • Llerena Schiffmacher, Diana A.;
    • Lee, Shun-Hsiao;
    • Kliza, Katarzyna W.;
    • Theil, Arjan F.;
    • Akita, Masaki;
    • Helfricht, Angela;
    • Bezstarosti, Karel;
    • Gonzalo-Hansen, Camila;
    • van Attikum, Haico;
    • Verlaan-de Vries, Matty;
    • Vertegaal, Alfred C. O.;
    • Hoeijmakers, Jan H. J.;
    • Marteijn, Jurgen A.;
    • Lans, Hannes;
    • Demmers, Jeroen A. A.;
    • Vermeulen, Michiel;
    • Sixma, Titia K.;
    • Ogi, Tomoo;
    • Vermeulen, Wim;
    • Pines, Alex
    Publication type:
    Article
    10
    11
    12
    13
    14

    Protein instability associated with AARS1 and MARS1 mutations causes trichothiodystrophy.

    Published in:
    Human Molecular Genetics, 2021, v. 30, n. 18, p. 1711, doi. 10.1093/hmg/ddab123
    By:
    • Botta, Elena;
    • Theil, Arjan F;
    • Raams, Anja;
    • Caligiuri, Giuseppina;
    • Giachetti, Sarah;
    • Bione, Silvia;
    • Accadia, Maria;
    • Lombardi, Anita;
    • Smith, Desiree E C;
    • Mendes, Marisa I;
    • Swagemakers, Sigrid M A;
    • Spek, Peter J van der;
    • Salomons, Gajja S;
    • Hoeijmakers, Jan H J;
    • Yesodharan, Dhanya;
    • Nampoothiri, Sheela;
    • Ogi, Tomoo;
    • Lehmann, Alan R;
    • Orioli, Donata;
    • Vermeulen, Wim
    Publication type:
    Article
    15
    16
    17

    The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.

    Published in:
    Frontiers in Aging, 2022, p. 1, doi. 10.3389/fragi.2022.1005322
    By:
    • Birkisdóttir, María B.;
    • van Galen, Ivar;
    • Brandt, Renata M. C.;
    • Barnhoorn, Sander;
    • van Vliet, Nicole;
    • van Dijk, Claire;
    • Nagarajah, Bhawani;
    • Imholz, Sandra;
    • van Oostrom, Conny T.;
    • Reiling, Erwin;
    • Gyenis, Ákos;
    • Mastroberardino, Pier G.;
    • Jaarsma, Dick;
    • van Steeg, Harry;
    • Hoeijmakers, Jan H. J.;
    • Dollé, Martijn E. T.;
    • Vermeij, Wilbert P.
    Publication type:
    Article
    18
    19
    20

    Cellular senescence drives age-dependent hepatic steatosis.

    Published in:
    Nature Communications, 2017, v. 8, n. 6, p. 15691, doi. 10.1038/ncomms15691
    By:
    • Ogrodnik, Mikolaj;
    • Miwa, Satomi;
    • Tchkonia, Tamar;
    • Tiniakos, Dina;
    • Wilson, Caroline L.;
    • Lahat, Albert;
    • Day, Christoper P.;
    • Burt, Alastair;
    • Palmer, Allyson;
    • Anstee, Quentin M.;
    • Grellscheid, Sushma Nagaraja;
    • Hoeijmakers, Jan H J.;
    • Barnhoorn, Sander;
    • Mann, Derek A.;
    • Bird, Thomas G.;
    • Vermeij, Wilbert P.;
    • Kirkland, James L.;
    • Passos, João F.;
    • von Zglinicki, Thomas;
    • Jurk, Diana
    Publication type:
    Article
    21
    22
    23
    24
    25

    From a DNA helicase to brittle hair.

    Published in:
    Nature Genetics, 1998, v. 20, n. 2, p. 106, doi. 10.1038/2396
    By:
    • Winkler, G. Sebastiaan;
    • Hoeijmakers, Jan H J
    Publication type:
    Article
    26

    Dietary restriction but not angiotensin II type 1 receptor blockade improves DNA damage-related vasodilator dysfunction in rapidly aging Ercc1<sup>Δ/−</sup> mice.

    Published in:
    Clinical Science, 2017, v. 131, n. 15, p. 1941, doi. 10.1042/CS20170026
    By:
    • Haiyan Wu;
    • van Thiel, Bibi S.;
    • Bautista-Niño, Paula K.;
    • Reiling, Erwin;
    • Durik, Matej;
    • Leijten, Frank P. J.;
    • Ridwan, Yanto;
    • Brandt, Renata M.C.;
    • van Steeg, Harry;
    • Dollé, Martijn E. T.;
    • Vermeij, Wilbert P.;
    • Hoeijmakers, Jan H. J.;
    • Essers, Jeroen;
    • van der Pluijm, Ingrid;
    • Danser, A. H. Jan;
    • Roks, Anton J. M.
    Publication type:
    Article
    27
    28

    A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.

    Published in:
    Nature, 2006, v. 444, n. 7122, p. 1038, doi. 10.1038/nature05456
    By:
    • Niedernhofer, Laura J.;
    • Garinis, George A.;
    • Raams, Anja;
    • Lalai, Astrid S.;
    • Robinson, Andria Rasile;
    • Appeldoorn, Esther;
    • Odijk, Hanny;
    • Oostendorp, Roos;
    • Ahmad, Anwaar;
    • van Leeuwen, Wibeke;
    • Theil, Arjan F.;
    • Vermeulen, Wim;
    • van der Horst, Gijsbertus T. J.;
    • Meinecke, Peter;
    • Kleijer, Wim J.;
    • Vijg, Jan;
    • Jaspers, Nicolaas G. J.;
    • Hoeijmakers, Jan H. J.
    Publication type:
    Article
    29
    30
    31

    Dietary Restriction Mitigates Vascular Aging, Modulates the cGAS‐STING Pathway and Reverses Macrophage‐Like VSMC Phenotypes in Progeroid DNA‐Repair‐Deficient Ercc1<sup>Δ</sup><sup>/−</sup> Mice.

    Published in:
    Aging Cell, 2025, v. 24, n. 7, p. 1, doi. 10.1111/acel.70062
    By:
    • Stefens, S. J. M.;
    • van der Linden, J.;
    • Heredia‐Genestar, J. M.;
    • Brandt, R. M. C.;
    • Barnhoorn, S.;
    • Nieuwenhuizen‐Bakker, I.;
    • van Vliet, N.;
    • Odijk, J. H. M.;
    • Ridwan, Y.;
    • Stuijts, D.;
    • Batenburg, M.;
    • Hoeijmakers, J. H. J.;
    • Kanaar, R.;
    • Essers, J.;
    • van der Pluijm, I.
    Publication type:
    Article
    32

    Different responses to DNA damage determine ageing differences between organs.

    Published in:
    Aging Cell, 2022, v. 21, n. 4, p. 1, doi. 10.1111/acel.13562
    By:
    • Vougioukalaki, Maria;
    • Demmers, Joris;
    • Vermeij, Wilbert P.;
    • Baar, Marjolein;
    • Bruens, Serena;
    • Magaraki, Aristea;
    • Kuijk, Ewart;
    • Jager, Myrthe;
    • Merzouk, Sarra;
    • Brandt, Renata M.C.;
    • Kouwenberg, Janneke;
    • van Boxtel, Ruben;
    • Cuppen, Edwin;
    • Pothof, Joris;
    • Hoeijmakers, Jan H. J.
    Publication type:
    Article
    33

    Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair‐deficient mice.

    Published in:
    Aging Cell, 2021, v. 20, n. 2, p. 1, doi. 10.1111/acel.13302
    By:
    • Birkisdóttir, María B.;
    • Jaarsma, Dick;
    • Brandt, Renata M. C.;
    • Barnhoorn, Sander;
    • Vliet, Nicole;
    • Imholz, Sandra;
    • Oostrom, Conny T.;
    • Nagarajah, Bhawani;
    • Portilla Fernández, Eliana;
    • Roks, Anton J. M.;
    • Elgersma, Ype;
    • Steeg, Harry;
    • Ferreira, José A.;
    • Pennings, Jeroen L. A.;
    • Hoeijmakers, Jan H. J.;
    • Vermeij, Wilbert P.;
    • Dollé, Martijn E. T.
    Publication type:
    Article
    34
    35
    36

    DNA damage in normally and prematurely aged mice.

    Published in:
    Aging Cell, 2013, v. 12, n. 3, p. 467, doi. 10.1111/acel.12071
    By:
    • Maslov, Alexander Y.;
    • Ganapathi, Shireen;
    • Westerhof, Maaike;
    • Quispe‐Tintaya, Wilber;
    • White, Ryan R.;
    • Van Houten, Bennett;
    • Reiling, Erwin;
    • Dollé, Martijn E. T.;
    • Steeg, Harry;
    • Hasty, Paul;
    • Hoeijmakers, Jan H. J.;
    • Vijg, Jan
    Publication type:
    Article
    37
    38
    39

    Supplementation with Lactobacillus plantarum WCFS1 Prevents Decline of Mucus Barrier in Colon of Accelerated Aging Ercc1<sup>−/Δ7</sup> Mice.

    Published in:
    Frontiers in Immunology, 2016, v. 7, p. 1, doi. 10.3389/fimmu.2016.00408
    By:
    • Meijer, Ben;
    • Hoogerland, Joanne A.;
    • Mihailova, Violeta;
    • van der Ploeg, Corine;
    • Savelkoul, Huub F. J.;
    • van Beek, Adriaan A.;
    • Leenen, Pieter J. M.;
    • Hendriks, Rudi W.;
    • Sovran, Bruno;
    • Wells, Jerry M.;
    • Hugenholtz, Floor;
    • Belzer, Clara;
    • Boekschoten, Mark V.;
    • de Vos, Paul;
    • Nicoletti, Claudio;
    • Vermeij, Wilbert P.;
    • Hoeijmakers, Jan H. J.
    Publication type:
    Article
    40
    41

    ERCC1-XPF Endonuclease Facilitates DNA Double-Strand Break Repair.

    Published in:
    Molecular & Cellular Biology, 2008, v. 28, n. 16, p. 5082, doi. 10.1128/MCB.00293-08
    By:
    • Ahmad, Anwaar;
    • Robinson, Andria Rasile;
    • Duensing, Anette;
    • van Drunen, Ellen;
    • Beverloo, H. Berna;
    • Weisberg, David B.;
    • Hasty, Paul;
    • Hoeijmakers, Jan H. J.;
    • Niedernhofer, Laura J.
    Publication type:
    Article
    42
    43
    44

    Differential Role of Basal Keratinocytes in UV-Induced Immunosuppression and Skin Cancer.

    Published in:
    Molecular & Cellular Biology, 2006, v. 26, n. 22, p. 26, doi. 10.1128/MCB.00807-06
    By:
    • Jans, Judith;
    • Garinis, George A.;
    • Schul, Wouter;
    • Van Oudenaren, Adri;
    • Moorhouse, Michael;
    • Smid, Marcel;
    • Sert, Yurda-Gul;
    • Van der Velde, Albertina;
    • Rijksen, Yvonne;
    • De Gruijl, Frank R.;
    • Van der Spek, Peter J.;
    • Yasui, Akira;
    • Hoeijmakers, Jan H. J.;
    • Leenen, Pieter J. M.;
    • Van der Horst, Gijsbertus T. J.
    Publication type:
    Article
    45
    46
    47
    48
    49
    50

    Correction: Impaired Genome Maintenance Suppresses the Growth HormoneInsulin-Like Growth Factor 1 Axis in Mice with Cockayne Syndrome.

    Published in:
    2008
    By:
    • van der Pluijm, Ingrid;
    • Garinis, George A.;
    • Brandt, Renata M. C.;
    • Gorgels, Theo G. M. F.;
    • Wijnhoven, Susan W.;
    • Diderich, Karin E. M.;
    • de Wit, Jan;
    • Mitchell, James R.;
    • van Oostrom, Conny;
    • Beems, Rudolf;
    • Niedernhofer, Laura J.;
    • Velasco, Susana;
    • Friedberg, Errol C.;
    • Tanaka, Kiyoji;
    • van Steeg, Harry;
    • Hoeijmakers, Jan H. J.;
    • van der Horst, Gijsbertus T. J.
    Publication type:
    Correction Notice