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- Title
Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat.
- Authors
D’Cruz, Patricia M.
- Abstract
Reports on a positional cloning approach to identification of the retinal dystrophy locus with the aim of gaining insight into the normal and abnormal interactions between the retinal pigment epithelial (RPE) cells and photoreceptor cells, and into the molecular mechanisms of outer segment ingestion by the RPE cells. Genetic evidence for an essential role of a receptor tyrosine kinase in a specialized form of phagocytosis.
- Publication
Human Molecular Genetics, 2000, Vol 9, Issue 4, p645
- ISSN
0964-6906
- Publication type
Academic Journal
- DOI
10.1093/hmg/9.4.645