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- Title
Clinical meaningfulness of the changes in muscle performance and physical function associated with testosterone administration in older men with mobility limitation.
- Authors
Travison, Thomas G; Basaria, Shehzad; Storer, Thomas W; Jette, Alan M; Miciek, Renee; Farwell, Wildon R; Choong, Karen; Lakshman, Kishore; Mazer, Norman A; Coviello, Andrea D; Knapp, Philip E; Ulloor, Jagadish; Zhang, Anqi; Brooks, Brad; Nguyen, Ahn-Hoa; Eder, Richard; LeBrasseur, Nathan; Elmi, Ayan; Appleman, Erica; Hede-Brierley, Leife; Bhasin, Geeta; Bhatia, Ashmeet; Lazzari, Antonio; Davis, Samuel; Ni, Pengsheng; Collins, Lauren; Bhasin, Shalender
- Abstract
Testosterone in Older Men with Mobility Limitations Trial determined the effects of testosterone on muscle performance and physical function in older men with mobility limitation. Trial's Data and Safety Monitoring Board recommended enrollment cessation due to increased frequency of adverse events in testosterone arm. The changes in muscle performance and physical function were evaluated in relation to participant's perception of change.
- Publication
The journals of gerontology. Series A, Biological sciences and medical sciences, 2011, Vol 66, Issue 10, p1090
- ISSN
1758-535X
- Publication type
Journal Article
- DOI
10.1093/gerona/glr100