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- Title
Methylenetetrahydrofolate reductase 677C>T and methionine synthase 2756A>G mutations: no impact on survival, cognitive functioning, or cognitive decline in nonagenarians.
- Authors
Bathum, Lise; von Bornemann Hjelmborg, Jacob; Christiansen, Lene; McGue, Matt; Jeune, Bernard; Christensen, Kaare
- Abstract
Several reports have shown an association between homocysteine, cognitive functioning, and survival among the oldest-old. Two common polymorphisms in the genes coding for methylenetetrahydrofolate reductase (MTHFR 677C>T) and methionine synthase (MTR 2756A>G) have an impact on plasma homocysteine level.
- Publication
The journals of gerontology. Series A, Biological sciences and medical sciences, 2007, Vol 62, Issue 2, p196
- ISSN
1079-5006
- Publication type
Journal Article
- DOI
10.1093/gerona/62.2.196