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- Title
Torcetrapib impairs endothelial function in hypertension.
- Authors
Simic, Branko; Hermann, Matthias; Shaw, Sidney G; Bigler, Laurent; Stalder, Urs; Dörries, Carola; Besler, Christian; Lüscher, Thomas F; Ruschitzka, Frank
- Abstract
A marked increase in HDL notwithstanding, the cholesterol ester transfer protein (CETP) inhibitor torcetrapib was associated with an increase in all-cause mortality in the ILLUMINATE trial. As underlying mechanisms remain elusive, the present study was designed to delineate potential off-target effects of torcetrapib.
- Publication
European heart journal, 2012, Vol 33, Issue 13, p1615
- ISSN
1522-9645
- Publication type
Journal Article
- DOI
10.1093/eurheartj/ehr348