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- Title
Cell isolation procedures matter: a comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction.
- Authors
Seeger, Florian H; Tonn, Torsten; Krzossok, Nicola; Zeiher, Andreas M; Dimmeler, Stefanie
- Abstract
The recently published REPAIR-AMI and ASTAMI trial showed differences in contractile recovery of left ventricular function after infusion of bone marrow-derived cells in acute myocardial infarction. Since the trials used different protocols for cell isolation and storage (REPAIR-AMI: Ficoll, storage in X-vivo 10 medium plus serum; ASTAMI: Lymphoprep, storage in NaCl plus plasma), we compared the functional activity of BMC isolated by the two different protocols.
- Publication
European heart journal, 2007, Vol 28, Issue 6, p766
- ISSN
0195-668X
- Publication type
Journal Article
- DOI
10.1093/eurheartj/ehl509