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- Title
A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction.
- Authors
Freyman, Toby; Polin, Glenn; Osman, Hashim; Crary, Jody; Lu, MinMin; Cheng, Lan; Palasis, Maria; Wilensky, Robert L
- Abstract
Mesenchymal stem cells (MSCs), rare bone marrow-derived stem cell precursors of non-haematopoietic tissues, have shown promise in potentially repairing infarcted myocardium. These and similar cell types are being tested clinically, but understanding of delivery and subsequent biodistribution is lacking. This study was designed to quantitatively compare MSC engraftment rates after intravenous (IV), intracoronary (IC), or endocardial (EC) delivery in a porcine myocardial infarction (MI) model.
- Publication
European heart journal, 2006, Vol 27, Issue 9, p1114
- ISSN
0195-668X
- Publication type
Journal Article
- DOI
10.1093/eurheartj/ehi818