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- Title
Changing neighbours, changing behaviour: cell adhesion molecule-mediated signalling during tumour progression.
- Authors
Christofori, Gerhard
- Abstract
Changes in cell-cell and cell-matrix adhesion accompany the transition from benign tumours to invasive, malignant cancer and the subsequent metastatic dissemination of tumour cells. This review discusses a possible role of cell adhesion molecules not only in redirecting a tumour cell's adhesive capabilities but also in modulating intracellular signalling, and with it, tumour malignancy.
- Publication
The EMBO journal, 2003, Vol 22, Issue 10, p2318
- ISSN
0261-4189
- Publication type
Journal Article
- DOI
10.1093/emboj/cdg228