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- Title
Immunomodulating Activity of Agaricus brasiliensis KA21 in Mice and in Human Volunteers.
- Authors
Ying Liu; Fukuwatari, Yasushi; Okumura, Ko; Takeda, Kazuyoshi; Ishibashi, Ken-ichi; Furukawa, Mai; Ohno, Naohito; Mori, Kazu; Ming Gao; Motoi, Masuro
- Abstract
We performed studies on murine models and human volunteers to examine the immunoenhancing effects of the naturally outdoor-cultivated fruit body of Agaricus brasiliensis KA21 (i.e. Agaricus blazei). Antitumor, leukocyte-enhancing, hepatopathy-alleviating and endotoxin shock-alleviating effects were found in mice. In the human study, percentage body fat, percentage visceral fat, blood cholesterol level and blood glucose level were decreased, and natural killer cell activity was increased. Taken together, the results strongly suggest that the A. brasiliensis fruit body is useful as a health-promoting food.
- Publication
Evidence-based Complementary & Alternative Medicine (eCAM), 2008, Vol 5, Issue 2, p205
- ISSN
1741-427X
- Publication type
Academic Journal
- DOI
10.1093/ecam/nem016