We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Redox-dependent increases in glutathione reductase and exercise preconditioning: role of NADPH oxidase and mitochondria.
- Authors
Frasier, Chad R; Moukdar, Fatiha; Patel, Hetal D; Sloan, Ruben C; Stewart, Luke M; Alleman, Rick J; La Favor, Justin D; Brown, David A
- Abstract
We have previously shown that exercise leads to sustainable cardioprotection through a mechanism involving improved glutathione replenishment. This study was conducted to determine if redox-dependent modifications in glutathione reductase (GR) were involved in exercise cardioprotection. Furthermore, we sought to determine if reactive oxygen species generated by NADPH oxidase and/or mitochondria during exercise were triggering events for GR modulations.
- Publication
Cardiovascular research, 2013, Vol 98, Issue 1, p47
- ISSN
1755-3245
- Publication type
Journal Article
- DOI
10.1093/cvr/cvt009