We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Serum-free differentiation of functional human coronary-like vascular smooth muscle cells from embryonic stem cells.
- Authors
El-Mounayri, Omar; Mihic, Anton; Shikatani, Eric A; Gagliardi, Mark; Steinbach, Sarah K; Dubois, Nicole; Dacosta, Ralph; Li, Ren-Ke; Keller, Gordon; Husain, Mansoor
- Abstract
Despite the diverse developmental origins of vascular smooth muscle cells (VSMCs), recent attempts to generate VSMCs from human embryonic stem cells (hESCs) differentiated along various lineages did not yield distinct cell phenotypes. The aim of this study was to derive and characterize functional coronary-like VSMCs from hESCs using serum-free cardiac-directed differentiation.
- Publication
Cardiovascular research, 2013, Vol 98, Issue 1, p125
- ISSN
1755-3245
- Publication type
Journal Article
- DOI
10.1093/cvr/cvs357