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- Title
Loss of ischaemic preconditioning in ovariectomized rat hearts: possible involvement of impaired protein kinase C epsilon phosphorylation.
- Authors
Shinmura, Ken; Nagai, Maiko; Tamaki, Kayoko; Bolli, Roberto
- Abstract
The aims of this study were to determine whether chronic oestrogen withdrawal influences the development of ischaemic preconditioning (IPC) in female hearts, to investigate the mechanism whereby IPC is impaired, and to assess whether direct activation of protein kinase C (PKC) can mimic IPC in female hearts with chronic oestrogen depletion.
- Publication
Cardiovascular research, 2008, Vol 79, Issue 3, p387
- ISSN
0008-6363
- Publication type
Journal Article
- DOI
10.1093/cvr/cvn086