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- Title
Effect of metoprolol and ivabradine on left ventricular remodelling and Ca2+ handling in the post-infarction rat heart.
- Authors
Maczewski, Michał; Mackiewicz, Urszula
- Abstract
beta-Blockers reduce mortality and morbidity in heart failure. Many of their benefits can be explained solely by heart rate reduction (HRR). We aimed to verify whether the beta-blocker, metoprolol, and the pure heart-rate-reducing agent, ivabradine, have the same effects on haemodynamic function, ventricular remodeling, and Ca2+ handling in post-myocardial infarction (MI) heart failure in rat.
- Publication
Cardiovascular research, 2008, Vol 79, Issue 1, p42
- ISSN
0008-6363
- Publication type
Journal Article
- DOI
10.1093/cvr/cvn057