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- Title
Early treatment with fluconazole may abrogate the development of IgG antibodies in coccidioidomycosis.
- Authors
Thompson, George R, 3rd; Lunetta, Jennine M; Johnson, Suzanne M; Taylor, Sandra; Bays, Derek; Cohen, Stuart H; Pappagianis, Demosthenes
- Abstract
We have observed a number of patients who fail to develop coccidioidal complement fixing (CF) antibody (immunoglobulin [IgG]) after the initiation of early antifungal therapy. Although this is the first description of this phenomenon in mycology, a precedent for the abrogation of the immune response has been observed in other conditions, including primary syphilis and primary Lyme disease.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2011, Vol 53, Issue 6, pe20
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1093/cid/cir466