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- Title
Virological response and HIV drug resistance 12 months after antiretroviral therapy initiation at 2 clinics in Nigeria.
- Authors
Ugbena, Richard; Aberle-Grasse, John; Diallo, Karidia; Bassey, Orji; Jelpe, Tapdiyel; Rottinghaus, Erin; Azeez, Aderemi; Akpan, Raphael; Muhammad, Mukhtar; Shanmugam, Vedapuri; Singh, Satvinder; Yang, Chunfu
- Abstract
This report describes a pilot study, conducted in Nigeria, of the World Health Organization protocol for monitoring human immunodeficiency virus (HIV) drug resistance (HIVDR) and associated program factors among patients receiving first-line antiretroviral therapy (ART). In 2008, 283 HIV-infected patients starting ART were consecutively enrolled at 2 ART clinics in Abuja. Twelve months after ART initiation, 62% were alive and on first-line ART, 3% had died, 1% had transferred out of the program, and 34% were lost to follow-up. Among patients on first-line ART at 12 months, 90% had viral suppression. However, in view of the high loss to follow-up rate (34%), strategies for patient retention and tracking are critical to minimize possible HIVDR and optimize treatment outcomes.
- Publication
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012, Vol 54 Suppl 4, pS375
- ISSN
1537-6591
- Publication type
Journal Article
- DOI
10.1093/cid/cir1064