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- Title
Haemodynamic effects of oxytocin given as i.v. bolus or infusion on women undergoing Caesarean section.
- Authors
Thomas, J S; Koh, S H; Cooper, G M
- Abstract
The cardiovascular effects of oxytocin in animal models and women undergoing Caesarean section include tachycardia, hypotension and decrease in cardiac output. These can be sufficient to cause significant compromise in high-risk patients. We aimed to find a simple way to decrease these risks whilst retaining the benefits of oxytocin in decreasing bleeding after delivery. Method. We recruited 30 women undergoing elective Caesarean section. They were randomly allocated to receive 5 u of oxytocin either as a bolus injection (bolus group) or an infusion over 5 min (infusion group). These women had their heart rate and intra-arterial blood pressure recorded every 5 s throughout the procedure. The haemodynamic data, along with the estimated blood loss, were compared between the groups.
- Publication
British journal of anaesthesia, 2007, Vol 98, Issue 1, p116
- ISSN
0007-0912
- Publication type
Journal Article
- DOI
10.1093/bja/ael302