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- Title
Inspired oxygen fraction of 0.8 compared with 0.4 does not further reduce postoperative nausea and vomiting in dolasetron-treated patients undergoing laparoscopic cholecystectomy.
- Authors
Piper, S N; Röhm, K D; Boldt, J; Faust, K L; Maleck, W H; Kranke, P; Suttner, S W
- Abstract
Postoperative nausea and vomiting (PONV) is one of the most frequent complications after general anaesthesia. Single-dose antiemetic prophylaxis has limited efficacy in high-risk patients. Adding a simple potential antiemetic approach, such as increasing the inspired oxygen fraction, to the antiemetic portfolio would preserve pharmacological interventions for treatment of symptoms in the postoperative period. However, the antiemetic effect of a high inspired oxygen fraction is still discussed controversially. The aim of the study was to evaluate whether an inspired oxygen fraction of 0.8 decreases PONV in patients receiving the 5-HT3-antagonist dolasetron.
- Publication
British journal of anaesthesia, 2006, Vol 97, Issue 5, p647
- ISSN
0007-0912
- Publication type
Journal Article
- DOI
10.1093/bja/ael242