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- Title
Activated recombinant factor VII after cardiopulmonary bypass reduces allogeneic transfusion in complex non-coronary cardiac surgery: randomized double-blind placebo-controlled pilot study.
- Authors
Diprose, P; Herbertson, M J; O'Shaughnessy, D; Gill, R S
- Abstract
Receiving an allogeneic transfusion may be an independent predictor of mortality for patients undergoing cardiac surgery. Furthermore, these patients utilize 15% of all donated blood in the UK. In our unit, 80% of patients undergoing complex non-coronary cardiac surgery requiring cardiopulmonary bypass (CPB) receive an allogeneic transfusion. Activated recombinant FVII (rFVIIa) may be effective in reducing this need for transfusion.
- Publication
British journal of anaesthesia, 2005, Vol 95, Issue 5, p596
- ISSN
0007-0912
- Publication type
Journal Article
- DOI
10.1093/bja/aei244