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- Title
STAR: ultrafast universal RNA-seq aligner.
- Authors
Dobin, Alexander; Davis, Carrie A; Schlesinger, Felix; Drenkow, Jorg; Zaleski, Chris; Jha, Sonali; Batut, Philippe; Chaisson, Mark; Gingeras, Thomas R
- Abstract
Accurate alignment of high-throughput RNA-seq data is a challenging and yet unsolved problem because of the non-contiguous transcript structure, relatively short read lengths and constantly increasing throughput of the sequencing technologies. Currently available RNA-seq aligners suffer from high mapping error rates, low mapping speed, read length limitation and mapping biases.
- Publication
Bioinformatics (Oxford, England), 2013, Vol 29, Issue 1, p15
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bts635