We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
RIsearch: fast RNA-RNA interaction search using a simplified nearest-neighbor energy model.
- Authors
Wenzel, Anne; Akbasli, Erdinç; Gorodkin, Jan
- Abstract
Regulatory, non-coding RNAs often function by forming a duplex with other RNAs. It is therefore of interest to predict putative RNA-RNA duplexes in silico on a genome-wide scale. Current computational methods for predicting these interactions range from fast complementary-based searches to those that take intramolecular binding into account. Together these methods constitute a trade-off between speed and accuracy, while leaving room for improvement within the context of genome-wide screens. A fast pre-filtering of putative duplexes would therefore be desirable.
- Publication
Bioinformatics (Oxford, England), 2012, Vol 28, Issue 21, p2738
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bts519