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- Title
MetiTree: a web application to organize and process high-resolution multi-stage mass spectrometry metabolomics data.
- Authors
Rojas-Chertó, Miguel; van Vliet, Michael; Peironcely, Julio E; van Doorn, Ronnie; Kooyman, Maarten; te Beek, Tim; van Driel, Marc A; Hankemeier, Thomas; Reijmers, Theo
- Abstract
Identification of metabolites using high-resolution multi-stage mass spectrometry (MS(n)) data is a significant challenge demanding access to all sorts of computational infrastructures. MetiTree is a user-friendly, web application dedicated to organize, process, share, visualize and compare MS(n) data. It integrates several features to export and visualize complex MS(n) data, facilitating the exploration and interpretation of metabolomics experiments. A dedicated spectral tree viewer allows the simultaneous presentation of three related types of MS(n) data, namely, the spectral data, the fragmentation tree and the fragmentation reactions. MetiTree stores the data in an internal database to enable searching for similar fragmentation trees and matching against other MS(n) data. As such MetiTree contains much functionality that will make the difficult task of identifying unknown metabolites much easier.
- Publication
Bioinformatics (Oxford, England), 2012, Vol 28, Issue 20, p2707
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bts486