We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Empirical Bayes conditional independence graphs for regulatory network recovery.
- Authors
Mahdi, Rami; Madduri, Abishek S; Wang, Guoqing; Strulovici-Barel, Yael; Salit, Jacqueline; Hackett, Neil R; Crystal, Ronald G; Mezey, Jason G
- Abstract
Computational inference methods that make use of graphical models to extract regulatory networks from gene expression data can have difficulty reconstructing dense regions of a network, a consequence of both computational complexity and unreliable parameter estimation when sample size is small. As a result, identification of hub genes is of special difficulty for these methods.
- Publication
Bioinformatics (Oxford, England), 2012, Vol 28, Issue 15, p2029
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/bts312