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- Title
Epigenetic priors for identifying active transcription factor binding sites.
- Authors
Cuellar-Partida, Gabriel; Buske, Fabian A; McLeay, Robert C; Whitington, Tom; Noble, William Stafford; Bailey, Timothy L
- Abstract
Accurate knowledge of the genome-wide binding of transcription factors in a particular cell type or under a particular condition is necessary for understanding transcriptional regulation. Using epigenetic data such as histone modification and DNase I, accessibility data has been shown to improve motif-based in silico methods for predicting such binding, but this approach has not yet been fully explored.
- Publication
Bioinformatics (Oxford, England), 2012, Vol 28, Issue 1, p56
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btr614