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Title
ChimeraScan: a tool for identifying chimeric transcription in sequencing data.
Authors
Iyer, Matthew K; Chinnaiyan, Arul M; Maher, Christopher A
Abstract
Next generation sequencing (NGS) technologies have enabled de novo gene fusion discovery that could reveal candidates with therapeutic significance in cancer. Here we present an open-source software package, ChimeraScan, for the discovery of chimeric transcription between two independent transcripts in high-throughput transcriptome sequencing data.