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- Title
Exploring metabolic pathways in genome-scale networks via generating flux modes.
- Authors
Rezola, A; de Figueiredo, L F; Brock, M; Pey, J; Podhorski, A; Wittmann, C; Schuster, S; Bockmayr, A; Planes, F J
- Abstract
The reconstruction of metabolic networks at the genome scale has allowed the analysis of metabolic pathways at an unprecedented level of complexity. Elementary flux modes (EFMs) are an appropriate concept for such analysis. However, their number grows in a combinatorial fashion as the size of the metabolic network increases, which renders the application of EFMs approach to large metabolic networks difficult. Novel methods are expected to deal with such complexity.
- Publication
Bioinformatics (Oxford, England), 2011, Vol 27, Issue 4, p534
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btq681