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- Title
The uniqueome: a mappability resource for short-tag sequencing.
- Authors
Koehler, Ryan; Issac, Hadar; Cloonan, Nicole; Grimmond, Sean M
- Abstract
Quantification applications of short-tag sequencing data (such as CNVseq and RNAseq) depend on knowing the uniqueness of specific genomic regions at a given threshold of error. Here, we present the 'uniqueome', a genomic resource for understanding the uniquely mappable proportion of genomic sequences. Pre-computed data are available for human, mouse, fly and worm genomes in both color-space and nucletotide-space, and we demonstrate the utility of this resource as applied to the quantification of RNAseq data.
- Publication
Bioinformatics (Oxford, England), 2011, Vol 27, Issue 2, p272
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btq640