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- Title
RNAsnoop: efficient target prediction for H/ACA snoRNAs.
- Authors
Tafer, Hakim; Kehr, Stephanie; Hertel, Jana; Hofacker, Ivo L; Stadler, Peter F
- Abstract
Small nucleolar RNAs are an abundant class of non-coding RNAs that guide chemical modifications of rRNAs, snRNAs and some mRNAs. In the case of many 'orphan' snoRNAs, the targeted nucleotides remain unknown, however. The box H/ACA subclass determines uridine residues that are to be converted into pseudouridines via specific complementary binding in a well-defined secondary structure configuration that is outside the scope of common RNA (co-)folding algorithms.
- Publication
Bioinformatics (Oxford, England), 2010, Vol 26, Issue 5, p610
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btp680