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- Title
Reconstructing spatiotemporal gene expression data from partial observations.
- Authors
Cartwright, Dustin A; Brady, Siobhan M; Orlando, David A; Sturmfels, Bernd; Benfey, Philip N
- Abstract
Developmental transcriptional networks in plants and animals operate in both space and time. To understand these transcriptional networks it is essential to obtain whole-genome expression data at high spatiotemporal resolution. Substantial amounts of spatial and temporal microarray expression data previously have been obtained for the Arabidopsis root; however, these two dimensions of data have not been integrated thoroughly. Complicating this integration is the fact that these data are heterogeneous and incomplete, with observed expression levels representing complex spatial or temporal mixtures.
- Publication
Bioinformatics (Oxford, England), 2009, Vol 25, Issue 19, p2581
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btp437