We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases–schizophrenia as a case.
- Authors
Jingchun Sun; Jia, Peilin; Fanous, Ayman H.; Webb, Bradley T.; Van den Oord, Edwin J.C.G.; Xiangning Chen; Bukszar, Jozsef; Kendler, Kenneth S.; Zhongming Zhao
- Abstract
Motivation: During the past decade, we have seen an exponential growth of vast amounts of genetic data generated for complex disease studies. Currently, across a variety of complex biological problems, there is a strong trend towards the integration of data from multiple sources. So far, candidate gene prioritization approaches have been designed for specific purposes, by utilizing only some of the available sources of genetic studies, or by using a simple weight scheme. Specifically to psychiatric disorders, there has been no prioritization approach that fully utilizes all major sources of experimental data.
- Publication
Bioinformatics, 2009, Vol 25, Issue 19, p2595
- ISSN
1367-4803
- Publication type
Academic Journal
- DOI
10.1093/bioinformatics/btp428