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- Title
SHREC: a short-read error correction method.
- Authors
Schröder, Jan; Schröder, Heiko; Puglisi, Simon J; Sinha, Ranjan; Schmidt, Bertil
- Abstract
Second-generation sequencing technologies produce a massive amount of short reads in a single experiment. However, sequencing errors can cause major problems when using this approach for de novo sequencing applications. Moreover, existing error correction methods have been designed and optimized for shotgun sequencing. Therefore, there is an urgent need for the design of fast and accurate computational methods and tools for error correction of large amounts of short read data.
- Publication
Bioinformatics (Oxford, England), 2009, Vol 25, Issue 17, p2157
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btp379