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- Title
SpliceAid: a database of experimental RNA target motifs bound by splicing proteins in humans.
- Authors
Francesco Piva; Matteo Giulietti; Linda Nocchi; Giovanni Principato
- Abstract
Summary: The correct post-transcriptional RNA processing is finely regulated by RNA-binding proteins. Unfortunately, there is little experimental information on target RNA sequences of RNA-binding proteins and moreover such experimentally derived target sequences are annotated in a compact form by the score matrices that overestimate the number of possible recognized sequences. We carried out an exhaustive hand curated literature search to create a database, SpliceAid, collecting all the experimentally assessed target RNA sequences that are bound by splicing proteins in humans. We built a web resource, database driven, to easy query SpliceAid and give back the results by an accurate and dynamic graphic representation. Availability: SpliceAid database is freely accessible at http://www.introni.it/splicing.html Contact: f.piva@univpm.it
- Publication
Bioinformatics, 2009, Vol 25, Issue 9, p1211
- ISSN
1367-4803
- Publication type
Academic Journal
- DOI
10.1093/bioinformatics/btp124