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- Title
CRONOS: the cross-reference navigation server.
- Authors
Waegele, Brigitte; Dunger-Kaltenbach, Irmtraud; Fobo, Gisela; Montrone, Corinna; Mewes, H-Werner; Ruepp, Andreas
- Abstract
Cross-mapping of gene and protein identifiers between different databases is a tedious and time-consuming task. To overcome this, we developed CRONOS, a cross-reference server that contains entries from five mammalian organisms presented by major gene and protein information resources. Sequence similarity analysis of the mapped entries shows that the cross-references are highly accurate. In total, up to 18 different identifier types can be used for identification of cross-references. The quality of the mapping could be improved substantially by exclusion of ambiguous gene and protein names which were manually validated. Organism-specific lists of ambiguous terms, which are valuable for a variety of bioinformatics applications like text mining are available for download.
- Publication
Bioinformatics (Oxford, England), 2009, Vol 25, Issue 1, p141
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btn590