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- Title
Ontologizer 2.0--a multifunctional tool for GO term enrichment analysis and data exploration.
- Authors
Bauer, Sebastian; Grossmann, Steffen; Vingron, Martin; Robinson, Peter N
- Abstract
The Ontologizer is a Java application that can be used to perform statistical analysis for overrepresentation of Gene Ontology (GO) terms in sets of genes or proteins derived from an experiment. The Ontologizer implements the standard approach to statistical analysis based on the one-sided Fisher's exact test, the novel parent-child method, as well as topology-based algorithms. A number of multiple-testing correction procedures are provided. The Ontologizer allows users to visualize data as a graph including all significantly overrepresented GO terms and to explore the data by linking GO terms to all genes/proteins annotated to the term and by linking individual terms to child terms.
- Publication
Bioinformatics (Oxford, England), 2008, Vol 24, Issue 14, p1650
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btn250