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- Title
gpDB: a database of GPCRs, G-proteins, effectors and their interactions.
- Authors
Theodoropoulou, Margarita C; Bagos, Pantelis G; Spyropoulos, Ioannis C; Hamodrakas, Stavros J
- Abstract
gpDB is a publicly accessible, relational database, containing information about G-proteins, G-protein coupled receptors (GPCRs) and effectors, as well as information concerning known interactions between these molecules. The sequences are classified according to a hierarchy of different classes, families and subfamilies based on literature search. The main innovation besides the classification of G-proteins, GPCRs and effectors is the relational model of the database, describing the known coupling specificity of GPCRs to their respective alpha subunits of G-proteins, and also the specific interaction between G-proteins and their effectors, a unique feature not available in any other database.
- Publication
Bioinformatics (Oxford, England), 2008, Vol 24, Issue 12, p1471
- ISSN
1367-4811
- Publication type
Journal Article
- DOI
10.1093/bioinformatics/btn206